Fig. 1.

TG synthesis and DNL in subcutaneous adipose tissue of obese IS and IR patients. A: Rate of TG synthesis per day (k), based on incorporation of ²H into glycerol moieties and labeling time (P < 0.001). B: Rate of de novo lipogenesis per day (k) based on incorporation of ²H into palmitate (P = 0.004). C: Rate of adipocyte proliferation per day (k) (P = 0.80). D: FFAs at fasting (P = 0.11). E: FFAs at steady-state (insulin infused at 60 μU/ml) (P = 0.059). Mean ± SD shown; P values were generated from log-transformed values and adjusted for BMI using ANCOVA analysis. Circles = male subjects; squares = female subjects.