Figure 2.

Chemopreventive effects of genistein against diverse cancers upon cancer development and progression. In 7,12-Dimethylbenz[a]anthracene (DMBA) induced carcinogenesis models using rodents, genistein has inhibitory effects by providing less sites for malignant transformation or upregulating a tumor suppressor gene. In addition, genistein has preventive effects against cancer progression such as cancer growth and metastasis in diverse animal models adopting transgenic and xenografted mice.