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Significantly differential methylation of 1582 promoter region CpG locations, in which the difference in mean methylation values between epithelial and stromal tissue was greater than or equal to 33%. Negative delta beta values indicate epithelial methylation, while positive delta beta values indicate stromal methylation. CpG methylation was greater in stromal tissue compared to epithelial tissue in 30 and 90 day xenografts.
