Skip to main content
. 2014 Dec 24;13(1):29–47. doi: 10.3390/md13010029

Figure 2.

Figure 2

Experimental design and timelines. Sham: Control animals underwent general anesthesia and sham surgical procedure without ischemia and hypoxia. HI: hypoxic-ischemic animals underwent ischemia induced by right common carotid artery occlusion followed by 100 min of hypoxia (8% oxygen balanced with 92% nitrogen). Xyl B + HI: hypoxic-ischemic animals with xyloketal B pretreatment 30 min prior to the onset of HI. Arrows: indicate the time of Xyl B or vehicle administration. Double arrows indicate the time that behavioral tests were conducted at 1 (P8), 3 (P10) and 7 (P14) days after the HI. P7 = postnatal 7 days; TTC stain was performed 24 h after HI at P8; TUNEL stain was performed 3 days after HI at P10; whole brain imaging and Nissl stain were performed 7 days after the HI at P14.