Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 19;13(1):655–665. doi: 10.3390/md13010655

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Topoisomerase II decatenation of kinetoplast-DNA (kDNA) assay. (a) doxorubicine (doxo) control: (1) size marker; (2) kDNA only; (3) kDNA + TopoII; (4) kDNA + TopoII + DMSO; (5) kDNA + TopoII + doxo 200 μM; (6) kDNA + TopoII + doxo 100 μM; (7) kDNA + TopoII + doxo 75 μM; (8) kDNA + TopoII + doxo 50 μM; (9) kDNA + TopoII + doxo 10 μM; (b) synthesized compounds test (1) size marker; (2) kDNA only; (3) kDNA + TopoII; (4) kDNA + TopoII + doxo 50 μM; (5) kDNA + TopoII + cmpd 1 100 μM; (6) kDNA + TopoII + cmpd 2 100 μM; (7) kDNA + TopoII + cmpd 3 100 μM; (8) kDNA + TopoII + cmpd 9 100 μM; (9) kDNA + TopoII + cmpd 7 100 μM; (10) kDNA + TopoII + cmpd 12 100 μM; (11) kDNA + TopoII + cmpd 11 100 μM; (12) kDNA + TopoII + cmpd 8 100 μM.