Table 2.
Relationship between haemoglobin at birth and primary outcomes (n = 890)
| Short term outcomes | Number (%) | Haemoglobin at birth (g/dL) | P values for trend | |||||
|---|---|---|---|---|---|---|---|---|
| OR | <12 | 12 to <14 | 14 to <16 | 16 to <18 | 18+ | |||
| (95% CI) | n = 67 | n = 124 | n = 122 | n = 408 | n = 169 | |||
| Deaths before discharge | 103 (11.6) | Crude | 19.5 (7.6–50.4) | 6.5 (2.6–16.5) | 2.8 (1.2–6.7) | 1.7 (0.5–5.0) | 1 | <0.01 |
| Adjusted† | 4.1 (1.4–11.6) | 2.0 (0.7–5.4) | 1.5 (0.6–3.7) | 1.7 (0.5–5.7) | 1 | 0.01 | ||
| Intraventricular haemorrhage (All grades) | 233 (26.2) | Crude | 4.2 (2.2–8.0) | 3.6 (2.1–6.2) | 2.1 (1.3–3.3) | 1.0 (0.5–1.8) | 1 | <0.01 |
| Adjusted† | 1.6 (0.8–3.3) | 1.9 (1.0–3.4) | 1.5 (1.0–2.4) | 0.9 (0.5–1.8) | 1 | 0.53 | ||
| Necrotising enterocolitis (All grades) | 195 (21.9) | Crude | 2.6 (1.3–5.1) | 3.2 (1.8–5.7) | 1.7 (1.0–2.8) | 1.1 (0.6–2.1) | 1 | <0.01 |
| Adjusted† | 1.0 (0.5–2.2) | 1.8 (1.0–3.4) | 1.3 (0.8–2.2) | 1.2 (0.6–2.3) | 1 | 0.31 | ||
| Bronchopulmonary dysplasia | 242 (27.2) | Crude | 3.1 (1.7–5.9) | 3.1 (1.8–5.3) | 2.0 (1.3–3.1) | 0.6 (0.3–1.1) | 1 | <0.01 |
| Adjusted† | 0.5 (0.3–1.1) | 1.0 (0.5–1.9) | 1.2 (0.7–2.0) | 0.5 (0.2–1.1) | 1 | 0.64 | ||
| Retinopathy of prematurity (All grades) | 185 (20.8) | Crude | 3.2 (1.5–6.4) | 4.9 (2.7–8.8) | 1.9 (1.2–3.2) | 0.9 (0.4–1.9) | 1 | <0.01 |
| Adjusted† | 0.7 (0.3–1.5) | 1.9 (1.0–3.8) | 1.2 (0.7–2.1) | 0.9 (0.4–2.0) | 1 | 0.72 | ||
†Adjusted odds ratio (OR) for gestational age and birth weight.