Table 2.
BB | HLA allele | Patients (N = 88) | Controls (N = 478) | p | pc | OR | IC | ||
---|---|---|---|---|---|---|---|---|---|
N | % | n | % | ||||||
B*49 | 0 | 0.00 | 29 | 6.07 | 0.014 | 0.448 | 0.09 | 0.005–1.42 | |
B*58 | 10 | 11.36 | 24 | 5.03 | 0.028 | 0.896 | 2.42 | 1.11–5.27 | |
C*05 | 5 | 5.68 | 67 | 14.02 | 0.035 | 0.49 | 0.37 | 0.14–0.94 | |
C*12 | 19 | 21.59 | 64 | 13.39 | 0.050 | 0.70 | 1.78 | 1.00–3.15 | |
BT | Patients (N = 70) | Controls (N = 478) | |||||||
A*33 | 8 | 11.43 | 25 | 5.23 | 0.056 | 1.12 | 2.34 | 1.01–5.41 | |
B*40 | 2 | 2.86 | 50 | 10.46 | 0.047 | 1.50 | 0.25 | 0.06–1.06 | |
B*49 | 0 | 0.00 | 29 | 6.07 | 0.039 | 1.24 | 0.11 | 0.006–1.79 | |
B*53 | 6 | 8.57 | 14 | 2.93 | 0.031 | 0.992 | 3.11 | 1.15–8.37 | |
C*05 | 3 | 4.28 | 67 | 14.02 | 0.020 | 0.28 | 0.27 | 0.08–0.89 | |
C*16 | 9 | 12.86 | 26 | 5.44 | 0.031 | 0.434 | 2.56 | 1.15–5.73 | |
DRB1*03 | 20 | 28.57 | 85 | 17.78 | 0.049 | 0.637 | 1.85 | 1.05–3.27 | |
BL | Patients (N = 44) | Controls (N = 478) | |||||||
B*53 | 4 | 9.09 | 14 | 2.93 | 0.056 | 1.792 | 3.31 | 1.04–10.54 | |
DRB1*07 | 5 | 11.36 | 128 | 26.77 | 0.028 | 0.364 | 0.35 | 0.13–0.91 | |
DQB1*02 | 8 | 18.18 | 189 | 39.53 | 0.005 | 0.025 | 0.34 | 0.15–0.75 |
N: number of individuals, n: number of alleles (2n), %: allele frequency, p: Fisher’s exact test (p ≤ 0.05), pc: corrected p value, OR: odds ratio, CI: confidence interval, boldface: significant association after Bonferroni´s correction.