Figure 10. Specific molecular changes occur in the transformed otd^−/− LALv1 lineage.

(A–C and G–I) document neuronal cell bodies of the wild-type LALv1 lineage immunolabelled with Acj6 (A–C) and Lim1 (G–I). The WT LALv1 neurons express both these molecular markers. (D–F and J–L) document neuronal cell bodies of the otd^−/− LALv1 lineage immunolabelled with Acj6 (D–F) and Lim1 (J–L). While otd^−/− LALv1 neurons continue to express Acj6 (E), they downregulate Lim1 expression (K).

DOI: http://dx.doi.org/10.7554/eLife.04407.018