Figure 12. Transformation of the LALv1 lineage.
(A) The WT LALv1 is a wide-field central complex lineage that expresses Otd (orange). (B) The loss of otd function from the LALv1 neuroblast transforms these neurons into antennal lobe projection neurons. This neuroanatomical transformation is accompanied by molecular changes—markers that are active in the WT LALv1 (green box in A) are suppressed in the mutant (B; with the exception of Acj6); those that are suppressed in the WT (red box in A), are activated in the mutant (B; with the exception of LN1-Gal4). The exceptions are in agreement with a transformation to antennal lobe projection neuron fate (see Table 1).