Table 2.

Clinical features and hemodynamic parameters of patients with each TPRC6 polymorphism

Clinical features and hemodynamic parameters	Carriers of c.1-361A > T mutation		Carriers of c.1-254C > G mutation		Carriers of c.1-218C > T mutation
	Clinical data	p-value	Clinical data	p-value	Clinical data	p-value
Number	32		37		32
Gender	25 F/7 M	0.002	23 F/14 M	0.177	11 F/21 M	0.035
Age at diagnosis (years)	50 ± 16	0.392	48 ± 16	0.403	52 ± 17	0.673
mPaP (mmHg)	50 ± 14	0.161	48 ± 14	0.162	48 ± 15	0.307
sPaP (mmHg)	71 ± 19	0.190	68 ± 18	0.195	70 ± 20	0.039
PVR (mmHg.l −1 .m −1 )	7.8 ± 2.3	0.336	7.6 ± 2.6	0.292	8 ± 2.8	0.027
CI (l.m −1 .m −2 )	2.6 ± 0.7	0.005	2.6 ± 0.6	0.016	2.6 ± 0.7	0.000
6MWT (m)	400 ± 160	0.136	423 ± 152	0.332	395 ± 141	0.168