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. 2015 Jan 16;16(1):4. doi: 10.1186/s12931-014-0162-6

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© Sureshbabu et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of TGFβ1 on lung apoptotic cell death. (A) TdT-mediated dUTP nick end labeling (TUNEL) was assessed in NB TGFβ1TG and TGFβ1TG X TGFβR2KO littermates where maternal dox exposure from PN7 – PN10 was carried out. Scale bar: 50 μm (B) Bar graph showing the percentage of TUNEL positive cells indicating the apoptosis quantification in TGFβ1TG mice and TGFβ1TG X TGFβR2KO littermates. (C) Representative serial sectioning images of cleaved caspase 3 and surfactant protein C staining in the lung specimens of TGFβ1TG mice and TGFβ1TG X TGFβR2KO littermates. Scale bar: 50 μm.