Table 3.

Univariate analysis on the time to xerostomia resolution or downgrade to GR1

Covariate	Stratification	HR	95% CI	p value
Age	Continuum	1.007	0.980-1.035	0.605
Sex	F vs M	0.679	0.243-1.900	0.461
AJCC stage	I-III vs IV	1.634	0.912-2.928	0.099
Induction + conc CHT	Yes vs No/Cet	0.519	0.162-1-659	0.269
Concomitant CHT	Yes vs No/Cet	0.556	0.295-1.050	0.070
Body Mass Index	Continuum	0.938	0.885-0.995	0.034
% PG Shrinkage at mid-tmt	Continuum	1.028	1.000-1.057	0.046
Smoking at diagnosis	Yes vs No	0.912	0.664-1.253	0.572
Smoking during follow up	Yes vs No	0.886	0.597-1.315	0.547
H- Mean PG pl-D	Continuum	0.962	0.930-0.995	0.023
L- Mean PG pl-D	Continuum	0.963	0.927-1.002	0.061
WA mean PG pl-D	Continuum	0.943	0.904-0.984	0.007
H- Mean SMG pl-D	Continuum	0.943	0.871-1.020	0.142
L- Mean SMG pl-D	Continuum	0.992	0.961-1.025	0.647
WA mean SMG pl-D	Continuum	0.981	0.935-1.030	0.436
WA mean PG + SMG pl-D	Continuum	0.944	0.904-0.987	0.011
Oral mucosa mean D	Continuum	0.991	0.951-1.033	0.674

Abbreviations: see Table 2; HR hazard ratio, CI confidence intervals, CHT chemotherapy, pl-D planning dose, F female, M male, PG parotid gland, SMG submandibular gland, WA weighted average.