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(A) TGF-β level in BALF and (B) MMP-2 relative mRNA expression level in lung tissue were determined at Day 14 after administration. Mice were exposed to ZnO nanoparticles with or without BLM treatment. The number of mice was six in the SALINE-no ZnO, seven in the SALINE-10 µg of ZnO, six in the SALINE-20 µg of ZnO, six in the BLM-no ZnO, six in the BLM-10 µg of ZnO and seven in the BLM-20 µg of ZnO group. Data are the means ± SD; * p < 0.05; compared to the vehicle control.
