Figure 4.

Effect of PW on MAPK phosphorylation in macrophages: (A) extracellular signal-regulated kinase (ERK); (B) p38 and (C) c-Jun NH₂-terminal kinase (JNK). RAW 264.7 cells were treated with PW for 30 min before incubation with LPS for 30 min. Cell lysates were analyzed using Western blot analysis with specific antibodies. The experiment was repeated three times independently and similar results were obtained. Con: control; Dex: Dexamethasone. ** p < 0.001 in comparisons of the LPS-stimulation value.