Table 2.
Expression of miR -143, -145, -7, -34a, and -21 in human colorectal cancer tissues as evaluated by performing TaqMan® Real-time PCR assays (clinical stage and Dukes’ system).
| Colorectal Cancer | n | miR-143 ↓ | miR-145 ↓ | miR-7 ↑ | miR-21 ↑ | miR-34a ↓ |
|---|---|---|---|---|---|---|
| clinical stage (Japanese Classificasion) | ||||||
| 0 | 27 | 20 | 21 | 12 | 14 | 16 |
| I | 31 | 23 | 23 | 22 | 19 | 11 |
| II | 31 | 18 | 20 | 27 | 11 | 21 |
| IIIa | 28 | 20 | 20 | 19 | 12 | 16 |
| IIIb | 7 | 6 | 7 | 4 | 2 | 5 |
| IV | 11 | 8 | 8 | 10 | 6 | 5 |
| p value | 0.6262 | 0.5328 | 0.0084 | 0.3230 | 0.1448 | |
| Dukes’s system | ||||||
| A or B | 92 | 63 | 66 | 63 | 45 | 49 |
| C | 43 | 32 | 33 | 31 | 19 | 25 |
| p value | 0.4813 | 0.5401 | 0.6705 | 0.6083 | 0.5957 |
Down arrow: down-regualted; Up arrow: up-regulated.