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Effects of ponicidin on ROS generation in MKN28 cells. (A) After treatment with ponicidin at doses of 10, 25 and 50 μmol/L for 1, 6, 24 and 48 h, cells were resuspended with 50 μmol/L DHE and analyzed by flow cytometry; and (B) Ponicidin treatment time- and dose-dependently increased ROS generation of MKN28 cells. # p < 0.01.
