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. 2015 Jan 12;16(1):1644–1656. doi: 10.3390/ijms16011644

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Cell viability assessed by MTT assay. Induction of NaIO₃ at the concentration of 3 and 3.5 mM can both reduce the viability of RPE cells. Mini-αA at the concentrations of 20 and 30 μM can both inhibit the reduction of cell viability caused by NaIO₃, with the best result achieved by mini-αA at the concentration of 20 μM. Control: normal ARPE-19 cells; mini-Αa-0: no mini-αA treatment before NaIO₃ induction; mini-Αa-20: treated with mini-αA at the concentration of 20 μM; mini-Αa-30: treated with mini-αA at the concentration of 30 μM. * p < 0.05 vs. mini-Αa-0.