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. Author manuscript; available in PMC: 2015 Jan 27.
Published in final edited form as: J Biopharm Stat. 2014;24(3):608–633. doi: 10.1080/10543406.2014.888437

Table V.

Correlation between estimates c1 and c2, and % Loss of Total Correct Classification

Scenario Method Correlation % Loss of Total Correct Classification
n=m=k=20 n=m=k=40 n=m=kl=80 n=50, m=35, k=25 n=m=k=20 n=m=k=40 n=m=k=80 n=50, m=35, k=25
1 Youden 0.147 0.147 0.129 0.124 - - - -
CP 0.539 0.550 0.527 0.524 1.81% 1.55% 1.28% 1.54%
Volume 0.573 0.621 0.570 0.592 1.50% 1.28% 1.06% 1.25%
2 Youden 0.254 0.206 0.175 0.205 - - - -
CP 0.589 0.711 0.706 0.594 2.71% 2.15% 1.83% 2.26%
Volume 0.766 0.748 0.757 0.767 2.29% 1.85% 1.62% 1.98%
3 Youden 0.229 0.218 0.232 0.235 - - - -
CP 0.652 0.656 0.670 0.695 1.70% 1.36% 1.16% 1.34%
Volume 0.611 0.599 0.591 0.652 1.80% 1.39% 1.18% 1.42%
4 Youden 0.166 0.194 0.197 0.223 - - - -
CP 0.415 0.447 0.425 0.417 1.73% 1.46% 1.28% 1.50%
Volume 0.520 0.517 0.454 0.495 1.05% 0.92% 0.81% 0.93%
5 Youden 0.294 0.208 0.162 0.259 - - - -
CP 0.393 0.342 0.312 0.356 1.33% 1.22% 1.09% 1.15%
Volume 0.462 0.421 0.391 0.444 0.70% 0.58% 0.45% 0.54%
6 Youden 0.057 −0.024 0.044 0.026 - - - -
CP 0.520 0.569 0.592 0.566 4.30% 4.45% 4.59% 4.40%
Volume 0.269 0.268 0.217 0.266 1.96% 1.79% 1.72% 1.92%

Youden = generalized Youden index, CP = closest to perfection, and Volume = max volume

The correlation and % loss of total classification estimates are described in sections 4.2 and 4.3 respectively.