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. 2014 Dec 15;7(12):4787–4798.

Figure 1.

Figure 1

IL1RAP was overexpressed on stem and progenitor cells of CML patients. Peripheral blood mononuclear cells of CML patients (n = 65) and healthy volunteers (n = 15) were isolated and stained for Flow cytometry analysis. A. Statistical analysis of IL1RAP expression in CD34+, CD34+CD38+, CD34+CD38- subsets from normal and CML patients respectively. *P < 0.05, **P < 0.01, n.s represents that there is no significant difference between groups. The bars represent the mean ± SD. B. FACS dot plots showed IL1RAP expression within three subsets from representative CML patients and normal blood samples. The data in each square presents the percentage of IL1RAP+ cells. C. An example of the gating strategy used for selecting CD34+CD38- and CD34+CD38+ cell population in normal and CML patients.