Table 3.
Effect of subchronic administration of EOE on serum biochemistry parameters
| Parameters | Group I | Group II | Group III | Group IV | Group V |
|---|---|---|---|---|---|
| Liver function test | |||||
| ALT (U/L) | 47.17 ± 8.47 | 53.17 ± 15.97 | 52.33 ± 12.56 | 60.00 ± 11.05 | 62.83 ± 11.58 |
| AST (U/L) | 156.83 ± 22.19 | 161.83 ± 22.07 | 179.00 ± 39.27 | 197.33 ± 39.27* | 208.83 ± 35.67* |
| TCH (mmol/L) | 2.09 ± 0.33 | 2.19 ± 0.37 | 2.21 ± 0.39 | 2.27 ± 0.38 | 2.08 ± 0.27 |
| TG (mmol/L) | 0.57 ± 0.07 | 0.47 ± 0.11 | 0.83 ± 0.26 | 0.76 ± 0.21 | 0.57 ± 0.74* |
| TP (g/L) | 75.73 ± 4.10 | 71.10 ± 4.44 | 73.7 ± 5.80 | 71.28 ± 1.47 | 71.47 ± 6.70 |
| Renal function test | |||||
| BUN (mmol/L) | 10.14 ± 2.46 | 11.57 ± 3.70 | 8.70 ± 0.94 | 10.68 ± 0.94 | 9.39 ± 2.26 |
| CRE (µmol/L) | 47.67 ± 7.79 | 48.83 ± 4.40 | 45.17 ± 6.62 | 56.67 ± 6.77* | 57.00 ± 8.17* |
| Serum electrolytes | |||||
| Na (mmol/L) | 140.33 ± 3.27 | 141.67 ± 2.07 | 132.67 ± 8.96* | 137.00 ± 1.67 | 135.00 ± 4.00 |
| K (mmol/L) | 5.70 ± 0.35 | 5.48 ± 0.57 | 5.63 ± 0.23 | 5.87 ± 0.34 | 5.56 ± 0.27 |
| Cl (mmol/L) | 104.83 ± 3.60 | 105.50 ± 1.52 | 98.67 ± 7.37* | 100.33 ± 2.07 | 97.83 ± 3.43* |
| Other test | |||||
| GLU (mmol/L) | 6.64 ± 0.73 | 7.04 ± 0.59 | 5.80 ± 0.62 | 5.19 ± 1.19* | 4.75 ± 0.48* |
| Alb (g/L) | 35.85 ± 4.08 | 34.75 ± 0.79 | 35.03 ± 3.34 | 34.35 ± 1.49 | 34.32 ± 0.95 |
The values are presented as means ± standard deviation (10 rats/sex/group). Alb, albumin; ALT, alanine aminotransferase; AST, aspartate transaminase; TP, total protein; BUN, blood urea nitrogen; GLU, glucose; CRE, Creatinine; TCH, total cholesterol; TG, triglycerides; Na, sodium; K, potassium; Cl, chlorine.
*
P < 0.05 shown there was significantly difference from control.