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. 2014 Dec 15;7(12):4867–4876.

Figure 3.

Figure 3

Effects of Ce6-PDT on cell proliferation and apoptosis of human colon cancer SW480 cells. SW480 cells were treated with Ce6 at 0, 0.125, 0.25, 0.5, 1.0, 2.0, 4.0, and 8.0 μg/ml, respectively, followed by photodynamic irradiation. SW480 cells treated with Ce6 at corresponding concentrations without photodynamic irradiation were used as controls. A. The cell survival rates of SW480 cells were assessed by the MTT assay. B-C. Cell apoptosis of SW480 cell was detected by the annexin-V/PI staining and flow cytometry. B. Representative results of flow cytometry indicating the apoptosis assessment of SW480 cells treated with Ce6-PDT at 0, 0.25, 1.0, and 4.0 μg/ml, respectively. C. Statistical analysis of apoptosis rates of SW480 cells treated with Ce6-PDT. Compared with the corresponding control group without photodynamic irradiation, *P < 0.05; compared with the previous group treated with Ce6-PDT, #P < 0.05.