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Development of mechanical allodynia post SNT surgery. Significant decrease of mechanical withdrawal threshold of model animals in vehicle group was observed throughout the observation period. Both propentofylline (10 mg/kg, i.p.) and safranal (0.1 mg/kg, i.p.) inhibited the development of mechanical allodynia at 7 and 21 d post surgery. $$$P < 0.001, compared to sham group; **P < 0.01, ***P < 0.001, #P < 0.05, compared to vehicle group.
