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RRM1 and hENT-1 expression association with chemotherapy response
| Clinical outcomes after chemotherapy | |||
|---|---|---|---|
|
|
|||
| Variables | SD+PR | PD | P |
| G | 5 (11.36%) | 4 (9.10%) | |
| G+FU/G+P | 4 (9.10%)/16 (36.37%) | 1 (2.27%)/14 (31.82%) | 0.932 |
| RRM1 | |||
| Negative | 16 (36.37%) | 6 (13.64%) | |
| Positive | 9 (20.45%) | 13 (29.55%) | 0.033 |
| hENT-1 | |||
| Negative | 7 (15.91%) | 11 (25.00%) | |
| Positive | 18 (40.91%) | 8 (18.18%) | 0.046 |
G, gemcitabine; FU, 5-fluorouracil; P, cis-platinum; PR, partial response; SD, stable disease; PD, progression disease.
