Table 2.
Adriamycin accumulation and retention in various cells
| Cell lines | Accumulations | Retention |
|---|---|---|
| Saos-2 | 61.5 ± 5.20 | 29.6 ± 3.17 |
| Saos-2-Ad-null | 59.6 ± 6.09 | 31.5 ± 2.96 |
| Saos-2-Ad-PDCD5 | 74.5 ± 6.92a | 36.8 ± 3.12a |
| Saos-2/ADM | 38.3 ± 3.51 | 20.4 ± 1.98 |
| Saos-2/ADM-Ad-null | 41.9 ± 5.52 | 21.6 ± 2.05 |
| Saos-2/ADM-Ad-PDCD5 | 67.4 ± 6.41b | 32.2 ± 3.86b |
Note: Adriamycin accumulation and retention were measured by flow cytometry, and intracellular Adriamycin concentration was represented by average fluorescence intensity. Values were represented as mean ± SD.
a
P < 0.05, compared with Saos-2-ad-null cells;
b
P < 0.05, compared with Saos-2/ADR-ad-null cells.