Table 2.
Relationship between HGF/c-Met expression and clinical and pathological parameters of NPC
| Parameter | c-Met expression Percentage of positive samples | χ2, P | HGF expression Percentage of positive samples | χ2, P | ||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||
| -- | +~+++ | (%) | -- | +~+++ | (%) | |||
| Sex | 0.81, 0.37 | 2.58, 0.11 | ||||||
| Male (n = 79) | 22 | 57 | 72.2 | 6 | 73 | 92.4 | ||
| Female (n = 27) | 10 | 17 | 63.0 | 5 | 22 | 81.5 | ||
| Age | 0.01, 0.90 | 3.62, 0.06 | ||||||
| < 50 (n = 72) | 22 | 50 | 69.4 | 7 | 65 | 90.3 | ||
| ≥ 50 (n = 34) | 10 | 24 | 70.6 | 4 | 30 | 88.2 | ||
| Histologic grade | 0.40, 0.53 | 1.32, 0.25 | ||||||
| DNKC (n = 82) | 26 | 56 | 68.3 | 7 | 75 | 91.5 | ||
| UNKC (n = 24) | 6 | 18 | 75.0 | 4 | 20 | 83.3 | ||
| Clinical stage | 13.03, < 0.01 | < 0.01* | ||||||
| I, II (n = 39) | 20 | 19 | 48.7 | 11 | 28 | 71.8 | ||
| III, IV (n = 67) | 12 | 55 | 82.1 | 0 | 67 | 100.0 | ||
| Cervical lymph node metastasis | 17.10, < 0.01 | 1.55, 0.21 | ||||||
| Positive (n = 83) | 17 | 66 | 79.5 | 7 | 76 | 91.6 | ||
| Negative (n = 23) | 15 | 8 | 34.8 | 4 | 19 | 82.6 | ||
*
Fisher’s exact test.