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Correlations of DPD gene 14G1A polymorphism with 5-FU side effect [n (%)]
| Side effect | Wild type (n=86) | Mutant type (n=14) | χ2 value | P value |
|---|---|---|---|---|
| Myelosuppression | 27 (31.4) | 8 (57.1) | 13.387 | 0.000 |
| Hand-foot syndrome | 24 (27.9) | 9 (64.3) | 26.661 | 0.000 |
| Diarrhea | 31 (36.1) | 11 (78.6) | 36.923 | 0.000 |
| Gastrointestinal reactions | 18 (20.9) | 9 (64.3) | 38.515 | 0.000 |
| Mucositis | 21 (24.4) | 7 (50.0) | 14.026 | 0.000 |
