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. 2014 Dec 23;8:460. doi: 10.1186/1752-1947-8-460

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© Abe et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Microscopic findings of the lung metastatic tumor at autopsy. (A) Hematoxylin and eosin stain. A transitional zone between the differentiated papillary pattern (left side of the image) and the undifferentiated component (right side of the image) is shown. (B, C, D) Immunohistochemical staining for thyroglobulin. Differentiated papillary carcinoma positive (B, arrowheads) and negative (C) for thyroglobulin and an undifferentiated component negative for thyroglobulin (D) are shown. (E, F) Immunohistochemical staining for thyroid transcription factor 1. Differentiated papillary carcinoma positive for thyroid transcription factor 1 (E) and an undifferentiated component positive for thyroid transcription factor 1 (F) are shown. Scale bars: 200μm (A-D), 50μm (E, F).