Table 3.
Infant neurological outcome by cocaine exposure during pregnancy.
| Infant Outcome | Cocaine-Unexposed (N=206) | Cocaine-Exposed (N=80) | P value | OR [95%CI] |
|---|---|---|---|---|
| Neurologic | ||||
| Microcephaly | 12 | 6 | .6 | 1.3 (.5–3.6) |
| Tremor* | 3 | 3 | .2 | 2.6 (.5–13.2) |
| Excessive startle* | 11 | 4 | .9 | .9 (.3–2.9) |
| Opistotonus | 8 | 4 | .7 | 1.3 (.7–4.5) |
| Hypertonia | 47 | 28 | .04 | 1.8 (1.02–2.1) |
| Extensor Posture | 57 | 36 | .008 | 2.0 (1.2–3.5) |
| Bilateral fisting | 11 | 11 | .02 | 2.7 (1.1–6.6) |
| Not Sitting | 17 | 12 | .08 | 2.0 (.91–4.4) |
| Poor Pincer Grasp | 26 | 21 | .01 | 2.2 (1.2–4.3) |
*
Exact significance two sided;
OR = Odds ratio; 95%CI= 95 percent confidence interval