. Author manuscript; available in PMC: 2015 Jan 27.

Published in final edited form as: Neurotoxicol Teratol. 2006 Dec 8;29(3):323–330. doi: 10.1016/j.ntt.2006.12.002

Table 4.

Infant neurological outcome by level of cocaine exposure

	Cocaine Unexposed (N=206)	Cocaine 1 CE1 (N=53)	COCAINE 2 CE2 (N=27)	P VALUE TREND	P VALUE Adjusted	ADJUSTED ODDS RATIO^* [95% CI]
Neurologic	N (%) OR	N (%) OR	N (%) OR
Global Hypertonia	48 (23) 1	17 (32) 1.5	11 (44) 4.3	.0005	.06	1.5 [.97–2.5]
Extensor Posture	58 (28) 1	23 (43) 2.0	12 (48) 2.4	.009	.03	1.6 [1.1–2.4]
Persistent Fisting	11 (5) 1	5 (9) 1.8	5 (24) 4.4	. 009	.02	1.9 [1.1– 3.7]

CE1 = Log riah <1.5; CE2 = Log riah ≥ 1.5. OR= Odds ratio; CI= confidence interval. Adjusted p value controlling for covariates in logistic regression models in which initial model includes gender, 5 minute Apgar score, corrected age, birth weight, prematurity, alcohol exposure, marijuana, and level of tobacco and cocaine exposure.

Adjusted analyses exclude 10 opiate exposed children.