Table 2.
The top ten disease terms for the “expert” gene set based on WebGestalt analysis. All reported disease terms had adjusted P values using the Benjamini & Hochberg correction for multiple testing <.001. All of these terms were also significantly enriched in the “all” gene set with P<.001 except “Intestinal neoplasms“ which had a corrected P value of .01 in that set.
| Disease term | Expert players (85 genes) | All (61 genes) | ||
|
|
Genes in set | Adjusted P value (BHa) |
Genes in set | Adjusted P value (BHa) |
| Cancer or viral infections | 37 | 5.5e-16 | 25 | 8.1e-10 |
| Neoplasms | 32 | 4.7e-13 | 22 | 1.6e-08 |
| Urogenital neoplasms | 23 | 2.7e-11 | 12 | 9.0e-05 |
| Cell transformation, neoplastic | 16 | 4.7e-11 | 13 | 3.0e-09 |
| Stomach neoplasms | 14 | 2.6e-08 | 8 | 2.0e-04 |
| Disease progression | 16 | 3.7e-08 | 13 | 2.5e-07 |
| Neoplastic processes | 20 | 5.1e-08 | 18 | 1.3e-08 |
| Recurrence | 14 | 5.1e-08 | 11 | 1.1e-06 |
| Intestinal neoplasms | 15 | 6.1e-08 | 6 | .01 |
| Necrosis | 15 | 1.1e-07 | 13 | 1.8e-07 |
aBH = Benjamini & Hochberg correction for multiple testing