Table 1.
Free VEGF-Trap | Bound VEGF | Free Rat VEGF | |
---|---|---|---|
VEGF-Trap | 98660 ± 11529 | 1540.45 ± 149.30 | 0.00 ± 0.00 |
BLQ | 359 | 309 | 783 |
Note: ELISA analysis was performed to assess the effectiveness of VEGF-Trap in attenuating the signaling of free rat VEGF. Blood serum levels were measured on day 11, after the last treatment. Free VEGF-Trap refers to unbound VEGF-Trap, Bound VEGF refers to VEGF/VEGF-Trap complex, Free Rat VEGF refers to unbound endogenous VEGF, and BLQ indicates Below Level of Quantification. Quantities are shown as group mean ± standard error (n=7). All units are ng/mL. VEGF levels for control animals were immeasurable and are not shown.