Table 3.

Results of the author’s analysis or reanalyzed (Wyatt, 1991) studies of early and delayed intervention with antipsychotic medications in first-episode schizophrenic patients

Study	Improvement of outcome between early versus delayed intervention
Astrup & Noreik (1966)	p<0.0001
Aritome (1978)	Inconclusive
Crow et al. (1986)	p=0.03 to 0.003
Anzai et al. (1988)	p=0.03
Loebel et al. (1992)	p=0.01 to 0.0001
Waddington et al. (1995)*	p=0.02
Szymanski et al. (1996)	p=0.0001

^*Patients were chronically ill but the difference appears to be related to prolonged delay in treatment.