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. 2015 Feb;6(1):20–31. doi: 10.1177/2042098614564776

Table 2.

Opioid acute withdrawal syndrome symptoms.

System organ class
 MEDRA preferred term
Cardiac disorders
 Tachycardia
Gastrointestinal disorders
 Diarrhea
 Nausea
 Vomiting
General disorders and administration site conditions
 Asthenia
 Chills
 Pain
 Pyrexia
Investigations
 Blood pressure increased
Nervous system disorders
 Tremor
Psychiatric disorders
 Nervousness
 Restlessness
Respiratory, thoracic and mediastinal disorders
 Rhinorrhea
 Sneezing
 Yawning
Skin and subcutaneous tissue disorders
 Hyperhidrosis
 Piloerection