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. 2015 Feb;6(1):20–31. doi: 10.1177/2042098614564776

Table 5.

Complications seen before or after naloxone administration (or patients may have never received naloxone) for acute intoxication with heroin or heroin mixtures (n = 538) [Osterwalder, 1996].

Event Number reported Percentage of 538 Resulting in death Percentage of 538
Cardiocirculatory arrest 9 1.7 5 0.9
Delayed onset of consciousness and normal respiration 8 1.5
Pulmonary edema 8 1.5 1 0.2
Aspiration 5 0.9
Hyperthermia 4 0.7
Generalized seizures 3 0.6 1* 0.2
Rhabdomyolysis 3 0.6
Pneumonia 2 0.3 2 0.3
Hypoglycemia 2 0.3
Hypothermia 2 0.3
*

Patient had asystole, hyperthermia (40°C) and hypoxemic encephalopathy before naloxone.