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. 2015 Feb;6(1):20–31. doi: 10.1177/2042098614564776

Table 6.

Events seen after naloxone administration in the prehospital setting [Yealy et al. 1990].

Event Number reported (percentage of 813) Comment
Generalized tonic-clonic seizure 1 (0.1%) Underlying seizure disorder
Vomiting 2 (0.2%) One patient received ipecac
Significant hypertension* 1 (0.1%) Total dose 1.2 mg
SBP increases > 30 mmHg 7 (0.9%) Systolic blood pressure (SBP) between 100 and 160 mmHg
Significant hypotension** 2 (0.2%)

No patient had ventricular tachycardia, fibrillation, or asystole; pulmonary edema was not assessed.

*

If SBP increased by more than 30 mmHg and above 160 mmHg.

**

If SBP decreased to less than 120 mmHg and dropped by 30 mmHg.