Abstract
Evidence is presented that demonstrates the absence of a measurable G2 phase in the cell cycles of two sublines of the Chinese hamster lung fibroblast V79. One of the sublines, in addition, lacks a detectable G1 phase, thereby possessing a cell cycle comprised of simply two phases, DNA synthesis (S) and mitosis (M).
Full text
PDF



Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Deaven L. L., Petersen D. F. The chromosomes of CHO, an aneuploid Chinese hamster cell line: G-band, C-band, and autoradiographic analyses. Chromosoma. 1973;41(2):129–144. doi: 10.1007/BF00319690. [DOI] [PubMed] [Google Scholar]
- ELKIND M. M., SUTTON H. Radiation response of mammalian cells grown in culture. 1. Repair of X-ray damage in surviving Chinese hamster cells. Radiat Res. 1960 Oct;13:556–593. [PubMed] [Google Scholar]
- FORD D. K., YERGANIAN G. Observations on the chromosomes of Chinese hamster cells in tissue culture. J Natl Cancer Inst. 1958 Aug;21(2):393–425. [PubMed] [Google Scholar]
- HAM R. G. CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM. Proc Natl Acad Sci U S A. 1965 Feb;53:288–293. doi: 10.1073/pnas.53.2.288. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mukherjee A. B. Cell cycle analysis and X-chromosome inactivation in the developing mouse. Proc Natl Acad Sci U S A. 1976 May;73(5):1608–1611. doi: 10.1073/pnas.73.5.1608. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PUCK T. T., STEFFEN J. LIFE CYCLE ANALYSIS OF MAMMALIAN CELLS. I. A METHOD FOR LOCALIZING METABOLIC EVENTS WITHIN THE LIFE CYCLE, AND ITS APPLICATION TO THE ACTION OF COLCEMIDE AND SUBLETHAL DOSES OF X-IRRADIATION. Biophys J. 1963 Sep;3:379–397. doi: 10.1016/s0006-3495(63)86828-9. [DOI] [PMC free article] [PubMed] [Google Scholar]
- QUASTLER H., SHERMAN F. G. Cell population kinetics in the intestinal epithelium of the mouse. Exp Cell Res. 1959 Jun;17(3):420–438. doi: 10.1016/0014-4827(59)90063-1. [DOI] [PubMed] [Google Scholar]
- Robbins E., Scharff M. D. The absence of a detectable G1 phase in a cultured strain of Chinese hamster lung cell. J Cell Biol. 1967 Aug;34(2):684–686. doi: 10.1083/jcb.34.2.684. [DOI] [PMC free article] [PubMed] [Google Scholar]
- STANNERS C. P., TILL J. E. DNA synthesis in individual L-strain mouse cells. Biochim Biophys Acta. 1960 Jan 29;37:406–419. doi: 10.1016/0006-3002(60)90496-0. [DOI] [PubMed] [Google Scholar]
- Sisken J. E., Iwasaki T. The effects of some amino acid analogs on mitosis and the cell cycle. Exp Cell Res. 1969 May;55(2):161–167. doi: 10.1016/0014-4827(69)90476-5. [DOI] [PubMed] [Google Scholar]
- Tobey R. A., Petersen D. F., Anderson E. C., Puck T. T. Life cycle analysis of mammalian cells. 3. The inhibition of division in Chinese hamster cells by puromycin and actinomycin. Biophys J. 1966 Sep;6(5):567–581. doi: 10.1016/s0006-3495(66)86678-x. [DOI] [PMC free article] [PubMed] [Google Scholar]