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PMA-stimulated ROS production in glomeruli from C57BL6/J mice infused subcutaneously with ET-1 (2pmol/kg/min) or saline for one week (osmotic mini-pump). Half of the animals were also treated with the ETA receptor antagonist, ABT-627 (5mg/kg/day) in drinking water. *P<0.05 vs. saline treated animals not treated with ABT-627.
