Table 2. Outcomes in infants alive with and without PH at 1,2,3,4, and 6 weeks.

	Death			Death or Prolonged Intubation (≥28 d)			Death or Prolonged Respiratory Support (≥56 d) or Home Oxygen*
	% Outcome (N)	P value	AUROC (95% CI)	% Outcome (N)	P value	AUROC (95% CI)	% Outcome (N)	P value	AUROC (95% CI)
Week 1 (n=136) §
With PH ¶(n=128)	18% (23/128)	p=0.35	0.73	25% (32/128)	p=0.20	0.72	41% (52/128)	p=0.023	0.7
Without PH (n=8)	0% (0/8)		(0.64, 0.82)	0% (0/8)		(0.65, 0.81)	0% (0/8)		(0.62, 0.79)
Week 2 (n=133)
With PH (n=86)	23% (20/86)	p<0.001	0.87	34% (29/86)	p<0.001	0.83	55% (47/86)	p<0.001	0.8
No PH (n=47)	0% (0/47)		(0.81, 0.94)	0% (0/47)		(0.75, 0.91)	6% (3/47)		(0.72, 0.88)
Week 3 (n=128)
With PH (n=55)	27% (15/55)	p<0.001	0.83	40% (22/55)	p<0.001	0.77	65% (36/55)	p<0.001	0.74
No PH (n=73)	0% (0/73)		(0.70, 0.95)	3% (2/73)		(0.64, 0.89)	12% (9/73)		(0.64, 0.83)
Week 4 (n=126)
With PH (n=46)	28% (13/46)	p<0.001	0.76	43% (20/46)	p<0.001	0.72	65% (30/46)	p<0.001	0.73
No PH (n=80)	0% (0/80)		(0.59, 0.93)	3% (2/80)		(0.58, 0.86)	16% (13/80)		(0.64, 0.83)
Week 6 (n=123)
With PH (n=34)	26% (9/34)	p<0.001	0.91	- -	-	-	62% (21/34)	p<0.001	0.63
No PH (n=89)	1% (1/89)		(0.80, 1.00)				21% (19/89)		(0.42, 0.82)

^*Per definition of bronchopulmonary dysplasia in infants >32 weeks gestational age [16]. Nine infants were discharged on O2 prior to 56 days median 37d, range 20-55)

^§Four infants died prior to one week echocardiogram

^¶PH is defined as as estimated pulmonary arterial pressures ≥2/3 systemic pressures

Abbreviations: AUROC - Area under the receiver operating curve; CI - confidence interval; PH - pulmonary hypertension