Table 2.
Tumor characteristics of HCC liver transplant recipients.
| Total Population (n=5002) |
Donor Age <60 (n=4162) |
Donor Age ≥60 (n=840) |
Local Share (n=3957) |
Non-local (n=1045) |
|||
|---|---|---|---|---|---|---|---|
|
Tumor Characteristics |
n (%) | n (%) | n (%) | p value | n (%) | n (%) | p value |
| Tumor number and size | |||||||
| >1 tumor all <2cm | 630 (12.6) | 504 (12.1) | 126 (15.0) | 0.02 | 493 (12.5) | 137 (13.1) | 0.57 |
| 1 tumor ≥2cm or multiple tumors with only 1 ≥2cm | 4077 (81.5) | 3424 (82.3) | 653 (77.7) | 0.002 | 3237 (81.8) | 840 (80.4) | 0.29 |
| 2–3 tumors ≥2cm | 295 (5.9) | 234 (5.6) | 61 (7.3) | 0.06 | 227 (5.7) | 68 (6.5) | 0.35 |
| Milan criteria at exception | 4946 (98.9) | 4117 (98.9) | 829 (98.7) | 0.57 | 3916 (99.0) | 1030 (98.6) | 0.28 |
| Ablative therapy at exception | 2167 (43.3) | 1827 (43.9) | 340 (40.5) | 0.07 | 1727 (43.6) | 440 (42.1) | 0.37 |
| AFP >500 ng/mL at exception | 293 (5.9) | 248 (6.0) | 45 (5.4) | 0.50 | 240 (6.1) | 53 (5.1) | 0.22 |
| HCC recurrence | 324 (6.5) | 244 (5.9) | 80 (9.5) | <0.001 | 236 (6.0) | 88 (8.4) | 0.004 |
| Non-HCC death | 866 (17.3) | 682 (16.4) | 184 (21.9) | <0.001 | 667 (16.9) | 199 (19.0) | 0.10 |
| Median (IQR) | Median (IQR) | Median (IQR) | p value | Median (IQR) | Median (IQR) | p value | |
| Total tumor volume at exception (cm3) | 9.2 (5.6–17.2) | 9.2 (5.6–17.2) | 9.7 (4.8–17.2) | 0.68 | 9.2 (5.6–17.2) | 9.4 (5.6–17.2) | 0.71 |
| Tumor size of main nodule (cm) | 2.4 (2.0–3.1) | 2.4 (2.0–3.1) | 2.3 (1.8–3.0) | 0.02 | 2.4 (2.0–3.1) | 2.4 (2.0–3.1) | 0.99 |