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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Magn Reson Med. 2014 Apr 18;73(3):1228–1236. doi: 10.1002/mrm.25232

Table 4.

Published R2’ values from comparable studies (young normal subjects scanned at 3T) and a study using the qBOLD approach with a multi-compartmental model (4). Note that R2’ values from (11) are approximate because the values were presented in graphical form only.

Reference Method Sample
Size		 Subject
Age		 GM R2’ (s−
1)		 WM R2’ (s−1) Comparison
to Our
Results
(10) Standard GESFIDE 6 19–42 3.4±1.1 (prefrontal cortex) 3.9±1.1 (frontal) Similar
(11) GESSE 6 Mean 25 - 1.5, inter-quartile range 0.9–1.7 (frontal) Lower
(12) Combined approach 21 Mean 36 9.2±1.1 (cortical) 9.3±1.1 (frontal) Higher
(13) Combined approach 66 total 18–84, linear regression analysis with age 7.4, 95% CI 6.6–8.1, (frontal cortex, 30 years old) 9.9, 95% CI 8.8–11.0, (frontal, 30 years old) Higher
(4) Multi-compartmental qBOLD 9 Unknown 2.9±0.4 0.68±0.10 Similar in GM Lower in WM