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. 2014 Dec 21;149(2):353–362. doi: 10.1007/s10549-014-3230-1

Table 3.

Relationship between PARP1 cleaved and non-cleaved with clinicopathological parameters

Variables PARP1 non-cleaved PARP1 cleaved
Negative n (%) Positive n (%) p value Negative n (%) Positive n (%) p value
Menopausal status
 Pre 182 (33.2) 216 (41.7) 0.004 65 (33.5) 409 (38.5) NS
 Post 366 (66.8) 302 (58.3) 129 (66.5) 653 (61.5)
Age
 <50 163 (29.7) 193 (36.9) 0.012 61 (31.4) 365 (34) NS
 ≥50 386 (70.3) 330 (63.1) 133 (68.6) 710 (66)
Tumour size
 ≤2 cm 279 (51.2) 240 (46.1) NS 96 (50) 523 (48.8) NS
 >2 cm 266 (48.8) 281 (53.9) 96 (50) 548 (51.2)
Tumour stage
 1 346 (62.9) 310 (59.5) NS 129 (66.5) 634 (59.2) NS
 2 159 (28.9) 164 (31.5) 51 (26.3) 342 (31.9)
 3 45 (8.2) 47 (9.0) 14 (7.2) 95 (8.9)
Tumour grade
 1 113 (20.7) 69 (13.3) 0.001 32 (16.7) 180 (17.9) NS
 2 180 (33) 163 (31.3) 61 (31.8) 368 (34.5)
 3 253 (46.3) 288 (55.4) 99 (51.6) 519 (48.6)
Tubule formation
 1 35 (6.7) 24 (4.7) NS 11 (5.9) 62 (6) NS
 2 181 (34.6) 160 (31.6) 57 (30.3) 336 (32.6)
 3 307 (58.7) 323 (63.7) 120 (63.8) 634 (61.4)
Pleomorphism
 1 14 (2.7) 10 (2) <0.001 1 (0.5) 29 (2.8) NS
 2 233 (44.6) 168 (33.1) 76 (40.4) 404 (39.2)
 3 275 (52.7) 329 (64.9) 111 (59) 598 (58)
Mitosis
 1 201 (38.4) 145 (28.6) 0.001 66 (35.1) 373 (36.1) NS
 2 103 (19.7) 95 (18.7) 30 (16) 200 (19.4)
 3 219 (41.9) 267 (52.7) 92 (48.9) 459 (44.5)
Vascular invasion
 Negative 185 (34) 174 (33.5) NS 65 (34) 355 (33.2) NS
 Positive 359 (66) 346 (66.5) 126 (66) 714 (66.8)
NPI groups
 Good 190 (34.9) 134 (25.7) 0.005 63 (32.8) 326 (30.4) NS
 Moderate 269 (49.4) 295 (56.6) 94 (49) 566 (52.8)
 Poor 86 (15.8) 92 (17.7) 35 (18.2) 179 (16.7)

Bold values indicate significance

NS not significant