Table 5.
Relationship between PARP1 non-cleaved and BRCA1 with DNA repair markers
| Marker | PARP1nc+/BRCA1− n (%) | PARP1nc−/BRCA1+ n (%) | p value | |
|---|---|---|---|---|
| CHK1 | Negative | 137 (52.3) | 125 (47.7) | 0.004 |
| Positive | 21 (32.3) | 44 (67.7) | ||
| DNA-PKcs | Negative | 12 (32.4) | 25 (67.6) | 0.003 |
| Positive | 116 (59.2) | 80 (40.8) | ||
| P53 | Negative | 99 (37.1) | 168 (62.9) | <0.001 |
| Positive | 78 (69.0) | 25 (31.0) | ||
| PIASγ | Negative | 25 (36.2) | 44 (63.8) | 0.013 |
| Positive | 143 (53.0) | 127 (47.0) | ||
| Ki67 | Negative | 25 (29.8) | 59 (70.2) | <0.001 |
| Positive | 130 (61.3) | 82 (47.6) |
Bold values indicate significance