Table 3. CYP2D6 activity scores of compliant patients.
|
Singapore (n=160) |
Lebanon (n=77) |
POSH (n=311) |
Overall (n=548) |
|||||
|---|---|---|---|---|---|---|---|---|
| CYP2D6 activity scores | No. of patients | % | No. of patients | % | No. of patients | % | No. of patients | % |
| 0.0 | 0 | 4 | 5.2 | 25 | 8.0 | 29 | 5.3 | |
| 0.5 | 12 | 7.5 | 4 | 5.2 | 28 | 9.0 | 44 | 8.0 |
| 0.75 | 52 | 32.5 | 2 | 2.6 | 7 | 2.25 | 61 | 11.1 |
| 1.0 | 13 | 8.1 | 15 | 19.5 | 95 | 30.5 | 123 | 22.4 |
| 1.5 | 48 | 30.0 | 15 | 19.5 | 53 | 17.0 | 116 | 21.2 |
| 2.0 | 32 | 20.0 | 27 | 35.1 | 102 | 32.8 | 161 | 29.4 |
| 3.0 | 1 | 0.6 | 10 | 13.0 | 1 | 0.3 | 12 | 2.2 |
| Unknown | 2 | 1.2 | 2 | 0.4 | ||||
Abbreviation: POSH, Prospective study of Outcomes in Sporadic versus Hereditary breast cancer.