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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Arthritis Rheumatol. 2014 Nov;66(11):3062–3072. doi: 10.1002/art.38780

Figure 5. Media analysis of iPSC-derived and native cartilage samples under inflammatory conditions.

Figure 5

(A) GAG release to the media increased in both tissues for IL-1α doses ≥100 pg/ml. (B) Specific MMP activity increased in a dose dependent manner at all concentrations. Concentration of nitric oxide (C) and PGE2 (C) increased following treatment with cytokine doses ≥100 pg/ml. A 1-way ANOVA was used with Tukey’s post-hoc test. Data are presented as mean ± SEM, and groups not connected by the same letter are significantly different from each other.