Figure 1.

Morphology of brain tissue in rats (hematoxylin-eosin staining, × 400).

In the cerebrum (A) and cerebellum (B) in sham surgery group, the configuration of neurons was clear, and there was no evidence of injury. The arrow shows a normal Purkinje's neuron.

(C, D) In the cortex of model group, the configuration of neurons was not clear, and local hemorrhaging was observed.

In the cerebellum (D), the metamorphosis of Purkinje neurons was observed (as shown by the arrow). Some Purkinje neurons were lost.