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Heroin users showed a decrease in blood-oxygen level-dependent signal in the prefrontal cortex, posterior cingulated cortex, and hippocampus compared with normal controls.
Concurrently, heroin users showed a significantly increased activation signal in the inferior parietal lobule (P < 0.05, corrected for false discovery rate).
Different colors represent varying degrees of activation. A cold color means negative activation while a warm color means positive activation.
