Table 1.

Pathways Analyzed and Percentage Showing Significant Clustering in Unmerged and Merged Data Sets

Organism	# Pathways analyzed	# Genes	% Significant unmerged data	% Significant merged data	% In random data
H. sapiens	98	975	78%	65%	11%
C. elegans	86	516	74%	58%	11%
D. melanogaster	85	484	50%	30%	12%
A. thaliana	79	318	60%	43%	11%
S. cerevisiae	89	682	100%	98%	10%

The percent significant refers to pathways in which the score is more than 3* (3rd quartile − median) + median. The same analysis was carried out on randomized pathways where genes were picked randomly from all genes, using the merged data.