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. 2015 Jan 22;15:2. doi: 10.1186/s12876-015-0227-0

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© Kang et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Association between miR-21 expression and recurrence-free survival in patients with T3-4a colorectal cancer. Kaplan-Meier survival curves for recurrence-free survival in all (A), stage II (B) and stage III (C) cancer patients according to miR-21 expression status. (A) High miR-21 expression is associated with recurrence-free survival in colon cancer patients but not in rectal cancer patients. (B) For the 138 patients with stage II cancer, the association between high miR-21 expression and recurrence-free survival is statistically significant only in colon cancer patients. (C) Among 277 stage III cancer patients, high miR-21 expression is not associated with poor recurrence-free survival.