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. 2015 Jan 29;17(1):4. doi: 10.1186/s12968-015-0107-3

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© Motwani et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Cyclic variation in MPR. Mean MPR in healthy volunteers (n = 30) showed significant cyclic variation throughout the cardiac cycle (p < 0.0001). Box plots for MPR show the interquartile range (box), median (dividing black line) and mean (red cross) with whiskers extending to 1.5 x interquartile range. There were successive reductions from end-diastole to early-, mid- and end-systole, and a significant increase from early- to end-diastole (all p values <0.01) (trend shown by red line). The maximal interval change in MPR was between end-systole and early diastole (31% increase). MPR = myocardial perfusion reserve.