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. 2003 May 1;13(5):896–904. doi: 10.1101/gr.440803

Table 2.

Top 50 Hypotheses for SGD Using Model MDT, Sorted Alphabetically by GO Attribute

Rating Gene name GO attribute
3 CUP5 C-actin cortical patch (sensu Saccharomyces)
3 UBC9 C-anaphase-promoting complex
1 SNR18 C-box C + D snoRNP protein (now obsolete)
1 SNR24 C-box C + D snoRNP protein (now obsolete)
3 SNR18 C-box H + ACA snoRNP protein (now obsolete)
2 RRP6 C-cytoplasmic exosome (RNase complex)
2 NHX1 C-hydrogen-translocating V-type ATPase
2 SRB8 C-mediator complex
3 IMG1 C-mitochondrial large ribosomal subunit
3 MRP8 C-mitochondrial large ribosomal subunit
3 YPL183W-A C-mitochondrial large ribosomal subunit
1 RPM2 C-ribonuclease P
2 CDC9 F-DNA-directed DNA polymerase
1 HXT1 F-fructose transporter
1 ANC1 F-general RNA polymerase II transcription factor
2 VPH2 F-hydrogen-transporting two-sector ATPase
1 DOA4 F-proteasome endopeptidase
2 NSA3 F-proteasome endopeptidase
1 RPN12 F-proteasome endopeptidase
1 RPN13 F-proteasome endopeptidase
1 RPN2 F-proteasome endopeptidase
3 MSP1 F-protein transporter
1 SSC1 F-protein transporter
1 SIN4 F-RNA polymerase II transcription mediator
3 DIM1 F-small nuclear ribonucleoprotein (now obsolete)
2 FMT1 F-translation initiation factor
2 UBI4 F-ubiquitin-specific protease
3 HRB1 P-35S primary transcript processing
1 RAT1 P-35S primary transcript processing
1 SEN1 P-35S primary transcript processing
3 UBP11 P-deubiquitylation
3 CPR4 P-ergosterol biosynthesis
3 CPR5 P-ergosterol biosynthesis
3 HSM3 P-leading strand elongation
3 KAR1 P-microtubule nucleation
2 MPS2 P-microtubule nucleation
2 DPB4 P-mismatch repair
2 TOM71 P-mitochondrial translocation
1 SPC72 P-mitotic chromosome segregation
3 UBC9 P-mitotic metaphase/anaphase transition
1 UBC9 P-mitotic spindle elongation
1 CLF1 P-mRNA splicing
3 NDC1 P-mRNA-nucleus export
3 SEC1 P-polar budding
1 BUB1 P-protein amino acid phosphorylation
1 IRE1 P-protein amino acid phosphorylation
1 VPS15 P-protein amino acid phosphorylation
3 SNR30 P-rRNA modification
2 IDP1 P-tricarboxylic acid cycle
3 ASM4 P-tRNA-nucleus export

The first column gives the curator's rating of each hypothesis, with 1 meaning “known to be true,” 2 meaning “known to be false,” and 3 meaning “neither of the above.”