Table 2.
Top 50 Hypotheses for SGD Using Model MDT, Sorted Alphabetically by GO Attribute
Rating | Gene name | GO attribute |
3 | CUP5 | C-actin cortical patch (sensu Saccharomyces) |
3 | UBC9 | C-anaphase-promoting complex |
1 | SNR18 | C-box C + D snoRNP protein (now obsolete) |
1 | SNR24 | C-box C + D snoRNP protein (now obsolete) |
3 | SNR18 | C-box H + ACA snoRNP protein (now obsolete) |
2 | RRP6 | C-cytoplasmic exosome (RNase complex) |
2 | NHX1 | C-hydrogen-translocating V-type ATPase |
2 | SRB8 | C-mediator complex |
3 | IMG1 | C-mitochondrial large ribosomal subunit |
3 | MRP8 | C-mitochondrial large ribosomal subunit |
3 | YPL183W-A | C-mitochondrial large ribosomal subunit |
1 | RPM2 | C-ribonuclease P |
2 | CDC9 | F-DNA-directed DNA polymerase |
1 | HXT1 | F-fructose transporter |
1 | ANC1 | F-general RNA polymerase II transcription factor |
2 | VPH2 | F-hydrogen-transporting two-sector ATPase |
1 | DOA4 | F-proteasome endopeptidase |
2 | NSA3 | F-proteasome endopeptidase |
1 | RPN12 | F-proteasome endopeptidase |
1 | RPN13 | F-proteasome endopeptidase |
1 | RPN2 | F-proteasome endopeptidase |
3 | MSP1 | F-protein transporter |
1 | SSC1 | F-protein transporter |
1 | SIN4 | F-RNA polymerase II transcription mediator |
3 | DIM1 | F-small nuclear ribonucleoprotein (now obsolete) |
2 | FMT1 | F-translation initiation factor |
2 | UBI4 | F-ubiquitin-specific protease |
3 | HRB1 | P-35S primary transcript processing |
1 | RAT1 | P-35S primary transcript processing |
1 | SEN1 | P-35S primary transcript processing |
3 | UBP11 | P-deubiquitylation |
3 | CPR4 | P-ergosterol biosynthesis |
3 | CPR5 | P-ergosterol biosynthesis |
3 | HSM3 | P-leading strand elongation |
3 | KAR1 | P-microtubule nucleation |
2 | MPS2 | P-microtubule nucleation |
2 | DPB4 | P-mismatch repair |
2 | TOM71 | P-mitochondrial translocation |
1 | SPC72 | P-mitotic chromosome segregation |
3 | UBC9 | P-mitotic metaphase/anaphase transition |
1 | UBC9 | P-mitotic spindle elongation |
1 | CLF1 | P-mRNA splicing |
3 | NDC1 | P-mRNA-nucleus export |
3 | SEC1 | P-polar budding |
1 | BUB1 | P-protein amino acid phosphorylation |
1 | IRE1 | P-protein amino acid phosphorylation |
1 | VPS15 | P-protein amino acid phosphorylation |
3 | SNR30 | P-rRNA modification |
2 | IDP1 | P-tricarboxylic acid cycle |
3 | ASM4 | P-tRNA-nucleus export |
The first column gives the curator's rating of each hypothesis, with 1 meaning “known to be true,” 2 meaning “known to be false,” and 3 meaning “neither of the above.”